bioRxiv

• ​Y. Li, S. Liu and F. Huang, "Variance lower bound on fluorescence microscopy image denoising" (2020) bioRxiv, doi: https://doi.org/10.1101/2020.05.13.094748

Publications

• S. Liu, Hyun Huh, Sang-Hyuk Lee†, and F. Huang†, "Three-Dimensional Single-Molecule Localization
  Microscopy in Whole-Cell and Tissue Specimens" (2020) Annual Review of Biomedical Engineering, 22:155–84. †co-corresponding authors
  

• S. Liu and F. Huang, "Enhanced 4Pi single-molecule localization microscopy with coherent pupil based localization" (2020) Communications Biology, 3, 220.

• F. Xu*, D. Ma*, K. P. MacPherson, S. Liu, Y. Bu, Y. Wang, Y. Tang, C. Bi, T. Kwok, A. A. Chubykin, P. Yin, S. Calve†, G. E. Landreth†, F. Huang†. “Three-dimensional nanoscopy of whole cells and tissues with in situ point spread function retrieval.” (2020) Nature Methods, 17, 531–540. *These authors contributed equally, †co-corresponding authors.

• S. An*, K. F. Ziegler*, P. Zhang, Y. Wang, T. Kwok, F. Xu, C. Bi, S. Matosevic, P. Yin, T. Li†, and F. Huang†, "Axial plane single-molecule super-resolution microscopy of whole cells" (2020) Biomedical Optics Express, ​ Vol.11, 1, pages  461-479. *These authors contributed equally. †co-corresponding authors.
• H. P. Babcock, F. Huang, C. M. Speer, "Correcting Artifacts in Single Molecule Localization Microscopy Analysis Arising from Pixel Quantum Efficiency Differences in sCMOS Cameras" (2019) Scientific Reports Vol.9 18058
• Y. Ren, Y. He, S. Brown, E. Zbornik, M. J. Mlodzianoski, D. Ma, F. Huang, S. Mattoo, and D. M. Suter, "A single tyrosine phosphorylation site in cortactin is important for filopodia formation in neuronal growth cones" (2019) Molecular Biology of the Cell, Vol. 30, 15, pages 1817-33, Cover story
• ​P. Zhang*, S. Liu*, A. Chaurasia, D. Ma, M. J. Mlodzianoski, E. Culurciello and F. Huang, "Analyzing complex single molecule emission patterns with deep learning"(2018) Nature Methods, Vol.15, 11, pages 913–916, *These authors contributed equally
• M. J. Mlodzianoski, P. J. Cheng-Hathaway, S. M. Bemiller, T. J. McCray, S. Liu, D. A. Miller, B. T. Lamb, G. E. Landreth, F. Huang, "Active PSF shaping and adaptive optics enable volumetric localization microscopy through brain sections" (2018) Nature Methods, Vol 15, 8, pages 583-586​
• Y. Ren, M. J. Mlodzianoski, A. C. Lee, F. Huang, and D. M. Suter, "A low-cost microwell device for high-resolution imaging of neurite outgrowth in 3D" (2018) J. Neural. Eng. 15:035001
• ​​S. Liu, M. J. Mlodzianoski, Z. Hu, Y. Ren, K. McElmurry, D. M. Suter, F. Huang, "sCMOS noise-correction algorithm for microscopy images" (2017) Nature Methods, Vol. 14, 8, 760 - 761.
• F. Huang*, G. Sirinakis*, E. S. Allgeyer, L. K. Schroeder, W. C. Duim, E. B. Kromann, T. Phan, F. E. Rivera-Molina, J. R. Myers, I. Irnov, M. Lessard, Y. Zhang, M. A. Handel, C. Jacobs-Wagner, C. P. Lusk, J. E. Rothman, D. Toomre, M. J. Booth, J. Bewersdorf, "Ultra-High Resolution 3D Imaging of Whole Cells" (2016) Cell, Vol. 166, 4, 1028 - 1040. *Equal contribution, Cover story
• C. Laplante, F. Huang, I. R. Tebbs, J. Bewersdorf, T. D. Pollard, "Molecular organization of cytokinesis nodes and contractile rings by super-resolution fluorescence microscopy of live fission yeast" (2016) PNAS, 113(40):E5876-E5885.
• F. del Viso*, F. Huang*, J. Myers, M. Chalfant, Y. Zhang, N. Reza, J. Bewersdorf, C. P. Lusk, M. K. Khokha "Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia" (2016) Developmental Cell, 38(5):478-92. *Equal contribution, Cover story
• C. Laplante, F. Huang, J. Bewersdorf, T. D. Pollard "High speed super resolution imaging of live fission yeast cells"​  (2015) Methods in Molecular Biology, Vol. 1390, pp. 45-57
• D. Burke, B. Patton, F. Huang, J. Bewersdorf, and M. Booth, "Adaptive optics correction of specimen-induced aberrations in single-molecule switching microscopy," (2015) Optica 2, 177-185 
• Y. Lin, J. J. Long, F. Huang, W. C. Duim, S. Kirschbaum, Y. Zhang, L. K. Schroeder, A. A. Rebane, M. G. M. Velasco, A. Virruet, D. W. Moonan, J. Jiao, S. Y. Hernandez, Y. Zhang, J. Bewersdorf, ‘Quantification and optimization of image quality in high speed single-molecule switching nanoscopy’, ​(2015) PLoS ONE 10(5): e0128135. 
• P. D. Uchil, T. Pawliczek, T. D. Reynolds, S. Ding, A. Hinz, J. Munro, F. Huang, R. W. Floyd, H. Yang, W. Hamilton, J. Bewersdorf, Y. Xiong, D.   A. Calderwood, W. Mothes, ‘TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly’, (2014) Journal of Cell Science, doi:10.1242/jcs.143537, 
• H. C. Lim, I. V. Surovtsev, B. G. Beltran, F. Huang, J. Bewersdorf, C. Jacobs Wagner, ‘Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregation’, (2014) eLife, 3. e02758 
• F. Huang, T. M. P. Hartwich, F. E. Rivera-Molina, Y. Lin, W. C. Duim, J. J. Long, P. D. Uchil, J. R. Myers, M. A. Baird, W. Mothes, M. W. Davidson, D. Toomre, J. Bewersdorf, ‘Video-Rate Nanoscopy Using sCMOS Camera-Specific Single-Molecule Localization Algorithms’, (2013) Nature Methods, 10, 653–658 
• Q. Yan, S. L. Schwartz, S. Maji, F. Huang, C. Szent-Gyorgyi, D. S. Lidke, K. A. Lidke, M. P. Bruchez, ‘Localization Microscopy using Noncovalent Fluorogen Activation by Genetically Encoded Fluorogen-Activating Proteins’,  (2013) ChemPhysChem, 15, 687 – 695
• F. Huang, S. L. Schwartz, J. M. Byars, K. A. Lidke, ‘Simultaneous multiple emitter fitting for single molecule super-resolution imaging’, (2011) Biomedical Optics Express, 2, 1377-1393 
• D. S. Lidke, F. Huang, J. N. Post, B. Rieger, J. Wilsbacher, J. L. Thomas, J. Pouysségur, T. M. Jovin, P. Lenormand, ‘ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation’, (2010) Journal of Biological Chemistry, 285, 3092-3102